From UCTV's website:
Robert H. Lustig, MD, UCSF Professor of Pediatrics in the Division of Endocrinology, explores the damage caused by sugary foods. He argues that fructose (too much) and fiber (not enough) appear to be cornerstones of the obesity epidemic through their effects on insulin.During his lecture, Dr. Lustig presents a compelling argument suggesting that biochemically, fructose (including high-fructose corn syrup) has long-term metabolic effects on the body as damaging as alcohol.
If you're not able to watch the whole 90 minute video in one shot, it's also available in 10 minute chunks on YouTube.
[h/t: Joey deVilla]